The Application of CRISPR-Cas System in Glioblastoma Research and Treatment
نویسندگان
چکیده
Glioblastoma is a malignant brain cancer with high mortality. Currently, there no effective treatment that can effectively improve the survival of patients. Traditional gene editing tools, such as Zinc finger nuclease, RNAi and translational activator-like effector nucleases (TALENTS), have shown their advantages in treating glioblastoma. However, they disadvantages cost difficult to operate. In recent years, discovery development CRISPR-Cas system, its easy design, inexpensive, flexibility make it gradually become widely used tool provide strong boost for research This article reviews literature summarizes application CRISPR Cas system model establishment therapy
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ژورنال
عنوان ژورنال: BIO web of conferences
سال: 2023
ISSN: ['2273-1709', '2117-4458']
DOI: https://doi.org/10.1051/bioconf/20236001011